Across TCGA patient cohorts, SLC38A3 mutation is significantly associated with the RNA expression of many other genes, with 2,660 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A3-associated genes across cancer lineages are EEF1E1-BLOC1S5, RNU6-718P, and RNU2-54P. Each is linked with SLC38A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC38A3-to-partner and partner-to-SLC38A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A3→partner) and Y-score (partner→SLC38A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	EEF1E1-BLOC1S5 →	+0.030	+2.596	<.001	.008	3	3
UCEC	RNU6-718P →	+0.107	+3.140	.004	.004	3	3
PRAD	RNU2-54P →	+0.249	+7.939	<.001	.008	3	2
UCEC	PRSS53 →	+0.277	+3.785	<.001	<.001	3	2
UCEC	CENPU →	+0.730	+2.280	<.001	.001	3	2
UCEC	BUB1B →	+0.726	+2.815	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,660 associations by consensus.

Exploration

SLC38A3 survival (RNA) · tumor vs normal (RNA) · all SLC38A3 data types