SLC38A10

Across TCGA patient cohorts, SLC38A10 mutation is significantly associated with the RNA expression of many other genes, with 1,891 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A10-associated genes across cancer lineages are JAKMIP1, RRM1, and TIMM21. Each is linked with SLC38A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC38A10-to-partner and partner-to-SLC38A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JAKMIP1 grouped by SLC38A10-low versus SLC38A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A10→partner) and Y-score (partner→SLC38A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JAKMIP1 →	+0.454	+4.021	<.001	<.001	3	3
UCEC	RRM1 →	+0.499	+1.347	.004	.007	3	3
UCEC	TIMM21 →	+0.330	+1.546	.004	.001	3	3
COAD	GOLGA3 →	+0.507	+3.210	.002	.009	3	3
UCEC	CDC6 →	+0.522	+1.627	.001	.004	3	3
UCEC	IL21R →	+0.477	+3.031	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,891 associations by consensus.

JAKMIP1 by SLC38A10 expression — UCEC

Explore this box plot interactively →