SLC38A10

Across TCGA pan-cancer cohorts, SLC38A10 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SLC38A10’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLC38A10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC38A10 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, KIRC, and LIHC are the cancer types where SLC38A10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC38A10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.845	<.001	11	view →
KIRC	Male	III,IV	+0.516	<.001	11	view →
LIHC	Female	II,III,IV	+0.871	<.001	9	view →
KICH	Male	All	−1.027	<.001	7	view →
THCA	Male	III,IV	−0.552	<.001	7	view →
LUAD	All	All	+0.299	.002	7	view →
STAD	Male	II,III,IV	+0.952	<.001	6	view →
BLCA	Female	III,IV	+0.802	.009	6	view →
CHOL	Male	All	+0.896	<.001	5	view →
PRAD	All	All	+0.281	.009	2	view →
ESCA	All	All	+0.492	.040	1	view →
COAD	Male	II,III,IV	+0.262	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

SLC38A10–HNSC

Open the HNSC breakdown →