SLC38A10

Across TCGA patient cohorts, SLC38A10 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A10-associated genes across cancer lineages are Caspase-7-cleavedD198, ASNS, and 4E-BP1. Each is linked with SLC38A10 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC38A10-to-partner and partner-to-SLC38A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by SLC38A10-low versus SLC38A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A10→partner) and Y-score (partner→SLC38A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.470	+1.785	.009	.007	3	4
COAD	ASNS →	+0.722	+2.815	<.001	.036	3	3
UCEC	4E-BP1 →	+0.236	+1.473	.004	.006	3	3
UCEC	Akt_pT308 →	+0.494	+1.999	.010	.008	3	2
UCEC	TIGAR →	+0.102	+1.289	.029	.012	3	2
SKCM	STAT3_pY705 →	-0.285	-2.321	.012	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Caspase-7-cleavedD198 by SLC38A10 expression — UCEC

Explore this box plot interactively →