SLC38A10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC38A10 mutation is significantly associated with the RNA expression of many other genes, with 397 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC38A10-associated genes across cancer lineages are LONP2, MYO5C, and RPAIN. Each is linked with SLC38A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A10-to-partner and partner-to-SLC38A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LONP2 grouped by SLC38A10-low versus SLC38A10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A10→partner) and Y-score (partner→SLC38A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaLONP2 →+0.399+3.351.007.00332
BLOOD_LeukemiaMYO5C →+1.146+3.351.003.00332
BLOOD_LeukemiaRPAIN →+0.619+3.470.002.00232
BLOOD_LeukemiaSCD5 →+1.574+3.351.003.00332
BLOOD_LeukemiaFBXO25 →+1.103+3.351.001.00332
BLOOD_LeukemiaRAB28 →+0.569+3.169.005.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 397 associations by consensus.

LONP2 by SLC38A10 expression — BLOOD_Leukemia

Box plot of LONP2 in SLC38A10-low vs SLC38A10-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration