SLC38A1

Across TCGA pan-cancer cohorts, SLC38A1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC38A1 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC38A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC38A1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where SLC38A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.762	1.000	.011	18	view →
PDAC	DFS	Median	All	0.298	0.581	.005	14	view →
CCRCC	OS	Median	All	0.768	0.875	.039	3	view →
GBM	DFS	Quartile	All	0.883	0.611	.019	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC38A1–LUAD (OS)

Open the LUAD breakdown →