SLC38A1

Across TCGA patient cohorts, SLC38A1 mutation is significantly associated with the RNA expression of many other genes, with 3,305 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A1-associated genes across cancer lineages are LMF2, SRGAP2C, and ESS2. Each is linked with SLC38A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC38A1-to-partner and partner-to-SLC38A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LMF2 grouped by SLC38A1-low versus SLC38A1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A1→partner) and Y-score (partner→SLC38A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LMF2 →	+0.653	+3.210	.002	.009	3	3
COAD	SRGAP2C →	+0.425	+3.210	.008	.009	3	3
UCEC	ESS2 →	+0.325	+4.000	<.001	<.001	3	3
UCEC	GNAI2 →	+0.367	+2.413	.002	<.001	3	3
UCEC	SDHB →	+0.418	+3.040	.001	<.001	3	3
UCEC	MESD →	+0.347	+2.617	.004	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,305 associations by consensus.

LMF2 by SLC38A1 expression — COAD

Explore this box plot interactively →