SLC38A1

Across TCGA cell cohorts, SLC38A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,114 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC38A1-associated GO terms across cancer lineages are L-glutamine import across plasma membrane, GABA metabolic process, and L-glutamine transport. Each is linked with SLC38A1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SLC38A1-to-partner and partner-to-SLC38A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-glutamine import across plasma membrane grouped by SLC38A1-low versus SLC38A1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A1→partner) and Y-score (partner→SLC38A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	L-glutamine import across plasma membrane →	+0.218	+1.522	.001	.001	3	18
BLOOD_Leukemia	GABA metabolic process →	+0.627	+2.340	<.001	<.001	3	10
BREAST	L-glutamine transport →	+0.105	+0.792	<.001	.001	2	10
LUNG_NSCLC_LUSC	Alanine transport →	+0.177	+0.936	.004	.009	2	10
SOFT_TISSUE	Negative regulation of RNA catabolic process →	+0.062	+1.510	<.001	.003	3	8
SOFT_TISSUE	Positive regulation of centriole elongation →	+0.054	+1.565	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,114 associations by consensus.

L-glutamine import across plasma membrane by SLC38A1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →