SLC38A1

Across TCGA cell cohorts, SLC38A1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC38A1-associated genes across cancer lineages are BTNL2, KRTAP10-1, and OR5V1. Each is linked with SLC38A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A1-to-partner and partner-to-SLC38A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTNL2 grouped by SLC38A1-low versus SLC38A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A1→partner) and Y-score (partner→SLC38A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	KRTAP10-1 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR5V1 →	+0.010	+5.022	<.001	.002	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
OVARY	PPY →	+0.222	+4.029	<.001	.009	3	1
OVARY	TAAR6 →	+0.884	+4.990	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

BTNL2 by SLC38A1 expression — LARGE_INTESTINE

Explore this box plot interactively →