SLC37A4

Across TCGA patient cohorts, SLC37A4 mutation is significantly associated with the RNA expression of many other genes, with 1,675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC37A4-associated genes across cancer lineages are SIGLEC24P, RNA5SP410, and RNA5SP411. Each is linked with SLC37A4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC37A4-to-partner and partner-to-SLC37A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC24P grouped by SLC37A4-low versus SLC37A4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC37A4→partner) and Y-score (partner→SLC37A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SIGLEC24P →	+0.034	+2.613	.009	.006	3	3
UCEC	RNA5SP410 →	+0.760	+2.789	<.001	<.001	3	3
UCEC	RNA5SP411 →	+1.099	+2.393	<.001	<.001	3	2
UCEC	RN7SL478P →	+0.207	+2.032	.001	.004	3	2
UCEC	SRP72P1 →	+0.151	+2.136	<.001	.006	3	2
COAD	OR5D14 →	+0.151	+6.153	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,675 associations by consensus.

SIGLEC24P by SLC37A4 expression — UCEC

Explore this box plot interactively →