SLC37A3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC37A3 mutation is significantly associated with the RNA expression of many other genes, with 2,860 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC37A3-associated genes across cancer lineages are RNA5SP457, RN7SL354P, and RNU6-1139P. Each is linked with SLC37A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC37A3-to-partner and partner-to-SLC37A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP457 grouped by SLC37A3-low versus SLC37A3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC37A3→partner) and Y-score (partner→SLC37A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNA5SP457 →+0.255+3.758.008.00833
STADRN7SL354P →+0.379+3.677.008.00733
STADRNU6-1139P →+0.543+4.991<.001<.00133
BLCACHMP1AP1 →+0.045+5.722<.001.00133
BLCAZNF863P →+0.158+3.758<.001.00833
UCECRN7SL248P →+0.064+3.059<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,860 associations by consensus.

RNA5SP457 by SLC37A3 expression — BLCA

Box plot of RNA5SP457 in SLC37A3-low vs SLC37A3-high samples in BLCA.

Explore this box plot interactively →

Exploration