SLC35G6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35G6 mutation is significantly associated with the RNA expression of many other genes, with 1,323 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35G6-associated genes across cancer lineages are RNU6-173P, TOMM22, and POLDIP3. Each is linked with SLC35G6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G6-to-partner and partner-to-SLC35G6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-173P grouped by SLC35G6-low versus SLC35G6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G6→partner) and Y-score (partner→SLC35G6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-173P →+0.187+2.937.002.00932
UCECTOMM22 →+0.557+3.828<.001<.00131
UCECPOLDIP3 →+0.599+3.850.001<.00131
UCECPACSIN2 →+0.663+3.343<.001.00531
UCECMYH9 →+0.529+2.711.009.00331
UCECPOLR3H →+0.454+3.467.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,323 associations by consensus.

RNU6-173P by SLC35G6 expression — UCEC

Box plot of RNU6-173P in SLC35G6-low vs SLC35G6-high samples in UCEC.

Explore this box plot interactively →

Exploration