SLC35G6

Across TCGA pan-cancer cohorts, SLC35G6 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of SLC35G6’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where SLC35G6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC35G6 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

UCEC, THCA, and LIHC are the cancer types where SLC35G6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC35G6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.091	.004	6	view →
THCA	Female	All	−0.145	<.001	5	view →
LIHC	All	II,III,IV	+0.032	.005	5	view →
CHOL	All	All	+0.110	<.001	3	view →
HNSC	All	All	+0.056	.011	3	view →
STAD	All	II,III,IV	+0.108	.031	2	view →
BRCA	All	IV	+0.024	.037	2	view →
LUSC	Female	II,III,IV	−0.094	.011	1	view →
KICH	All	II,III,IV	+0.065	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

SLC35G6–UCEC

Open the UCEC breakdown →