SLC35G5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35G5 mutation is significantly associated with the RNA expression of many other genes, with 660 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35G5-associated genes across cancer lineages are RNU6-271P, RPL22P14, and RNA5SP516. Each is linked with SLC35G5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G5-to-partner and partner-to-SLC35G5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-271P grouped by SLC35G5-low versus SLC35G5-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G5→partner) and Y-score (partner→SLC35G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READRNU6-271P →+0.592+5.653<.001.00332
LIHCRPL22P14 →+0.142+5.544<.001.00432
UCECRNA5SP516 →+0.156+2.545.001.00532
UCECRNU6-1064P →+0.400+1.623.003.00532
UCECSURF6P1 →+0.019+2.847<.001.00832
UCECSYNJ2BP-COX16 →+0.209+3.532<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 660 associations by consensus.

RNU6-271P by SLC35G5 expression — READ

Box plot of RNU6-271P in SLC35G5-low vs SLC35G5-high samples in READ.

Explore this box plot interactively →

Exploration