SLC35G5

Across TCGA patient cohorts, SLC35G5 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35G5-associated genes across cancer lineages are Caspase-8, Chk1_pS345, and 14-3-3_beta. Each is linked with SLC35G5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G5-to-partner and partner-to-SLC35G5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-8 grouped by SLC35G5-low versus SLC35G5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G5→partner) and Y-score (partner→SLC35G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-8 →	-0.215	-3.143	.033	.018	3	2
UCEC	Chk1_pS345 →	+0.167	+1.498	.002	.036	3	2
UCEC	14-3-3_beta →	-0.122	-3.432	.002	.005	3	1
UCEC	eIF4E →	+0.194	+3.183	.022	.009	3	1
UCEC	A-Raf_pS299 →	-0.155	-2.700	.001	.006	3	1
UCEC	ERK2 →	+0.216	+2.415	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Caspase-8 by SLC35G5 expression — UCEC

Explore this box plot interactively →