SLC35G5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35G5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC35G5-associated genes across cancer lineages are LCE3E, FAM25A, and ADH7. Each is linked with SLC35G5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G5-to-partner and partner-to-SLC35G5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE3E grouped by SLC35G5-low versus SLC35G5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G5→partner) and Y-score (partner→SLC35G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaLCE3E →+0.020+4.984<.001.00231
BLOOD_LeukemiaFAM25A →+0.057+4.060.006.00331
BLOOD_LeukemiaADH7 →+0.065+3.944<.001.00631
BLOOD_LeukemiaDPRX →+0.063+4.060<.001.00331
BLOOD_LeukemiaHNRNPCL3 →+0.031+3.874<.001.00531
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

LCE3E by SLC35G5 expression — BLOOD_Leukemia

Box plot of LCE3E in SLC35G5-low vs SLC35G5-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration