SLC35G2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35G2 mutation is significantly associated with the RNA expression of many other genes, with 1,576 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35G2-associated genes across cancer lineages are GPATCH11, USP12, and TBRG1. Each is linked with SLC35G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G2-to-partner and partner-to-SLC35G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPATCH11 grouped by SLC35G2-low versus SLC35G2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G2→partner) and Y-score (partner→SLC35G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGPATCH11 →+0.632+2.818<.001.00132
UCECUSP12 →+0.622+2.756<.001.00232
UCECTBRG1 →+0.514+3.732<.001<.00132
UCECHSPA13 →+0.738+3.475.001.00232
UCECPRRC1 →+0.736+3.606<.001.00132
UCECZNF701 →+0.442+3.641.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,576 associations by consensus.

GPATCH11 by SLC35G2 expression — UCEC

Box plot of GPATCH11 in SLC35G2-low vs SLC35G2-high samples in UCEC.

Explore this box plot interactively →

Exploration