SLC35G1

Across TCGA patient cohorts, SLC35G1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35G1-associated genes across cancer lineages are VHL, ATM, and ERK2. Each is linked with SLC35G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35G1-to-partner and partner-to-SLC35G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VHL grouped by SLC35G1-low versus SLC35G1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35G1→partner) and Y-score (partner→SLC35G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VHL →	-0.793	-2.459	.004	.019	3	2
UCEC	ATM →	-0.480	-3.169	.010	.019	3	2
UCEC	ERK2 →	+0.173	+2.999	.029	.035	3	1
UCEC	FOXO3a →	-0.109	-1.794	.009	.027	3	1
UCEC	JNK_pT183_Y185 →	-0.198	-2.986	.004	.001	3	1
UCEC	JNK2 →	+0.220	+2.321	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

VHL by SLC35G1 expression — UCEC

Explore this box plot interactively →