SLC35F4

Across TCGA patient cohorts, SLC35F4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,140 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SLC35F4-associated GO terms across cancer lineages are Smoothened signaling pathway, Protein-containing complex disassembly, and Regulation of microtubule cytoskeleton organization. Each is linked with SLC35F4 in more than 23 cancer types. Because this analysis shows association rather than direction, both SLC35F4-to-partner and partner-to-SLC35F4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Smoothened signaling pathway grouped by SLC35F4-low versus SLC35F4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F4→partner) and Y-score (partner→SLC35F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Smoothened signaling pathway →	+0.052	+0.108	<.001	<.001	3	24
STAD	Protein-containing complex disassembly →	+0.067	+0.122	<.001	<.001	3	22
SCLC	Regulation of microtubule cytoskeleton organization →	+0.085	+1.041	<.001	<.001	3	22
STAD	mRNA transport →	+0.071	+0.096	<.001	<.001	3	21
STAD	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.074	+0.108	<.001	<.001	3	21
SCLC	Microtubule polymerization or depolymerization →	+0.097	+0.920	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,140 associations by consensus.

Smoothened signaling pathway by SLC35F4 expression — STAD

Explore this box plot interactively →