SLC35F4

Across TCGA patient cohorts, SLC35F4 mutation is significantly associated with the RNA expression of many other genes, with 2,117 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F4-associated genes across cancer lineages are TIPIN, EMID1, and SLX4. Each is linked with SLC35F4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC35F4-to-partner and partner-to-SLC35F4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIPIN grouped by SLC35F4-low versus SLC35F4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F4→partner) and Y-score (partner→SLC35F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIPIN →	+0.415	+2.158	.001	<.001	3	4
UCEC	EMID1 →	-1.605	-2.512	<.001	<.001	3	3
UCEC	SLX4 →	+0.453	+3.850	<.001	<.001	3	3
UCEC	CDKN3 →	+0.580	+3.700	.005	.001	3	3
UCEC	DHODH →	+0.275	+2.362	.007	.003	3	3
LUSC	ACOT2 →	+0.607	+3.596	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,117 associations by consensus.

TIPIN by SLC35F4 expression — UCEC

Explore this box plot interactively →