SLC35F4

Across TCGA patient cohorts, SLC35F4 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35F4-associated genes across cancer lineages are Caspase-7-cleavedD198, 4E-BP1, and Di-Ras3. Each is linked with SLC35F4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F4-to-partner and partner-to-SLC35F4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by SLC35F4-low versus SLC35F4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F4→partner) and Y-score (partner→SLC35F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.510	+3.341	.022	.005	3	2
UCEC	4E-BP1 →	+0.311	+3.489	.002	.002	3	2
UCEC	Di-Ras3 →	-0.140	-3.308	.012	.009	3	2
LUSC	Rb_pS807_S811 →	+0.682	+2.816	.004	.036	3	1
SKCM	IRS1 →	+0.238	+1.906	<.001	.014	3	1
SKCM	Myosin-IIa_pS1943 →	-0.309	-1.397	.003	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Caspase-7-cleavedD198 by SLC35F4 expression — UCEC

Explore this box plot interactively →