SLC35F4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35F4 RNA expression is significantly associated with the go_rna of many other GO terms, with 632 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC35F4-associated GO terms across cancer lineages are Regulation of intracellular protein transport, Negative regulation of telomere maintenance via telomerase, and Positive regulation of RNA polymerase II transcription preinitiation complex assembly. Each is linked with SLC35F4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC35F4-to-partner and partner-to-SLC35F4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular protein transport grouped by SLC35F4-low versus SLC35F4-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F4→partner) and Y-score (partner→SLC35F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADRegulation of intracellular protein transport →+0.041+0.052.005.00425
PANCREASNegative regulation of telomere maintenance via telomerase →+0.041+0.167.001.00234
LUNG_SCLCPositive regulation of RNA polymerase II transcription preinitiation complex assembly →+0.114+1.064.009.00434
PANCREASNegative regulation of DNA biosynthetic process →+0.068+0.125<.001.00133
URINARY_TRACTRegulation of macropinocytosis →-0.143-0.060.004.00933
LUNG_SCLCMicrotubule-based transport →+0.058+1.693.003<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 632 associations by consensus.

Regulation of intracellular protein transport by SLC35F4 expression — LUNG_NSCLC_LUAD

Box plot of Regulation of intracellular protein transport in SLC35F4-low vs SLC35F4-high samples in LUNG_NSCLC_LUAD.

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Exploration