SLC35F4

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35F4 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35F4-associated genes across cancer lineages are CCT245467, FY012, and JAK3_7406. Each is linked with SLC35F4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35F4-to-partner and partner-to-SLC35F4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCT245467 grouped by SLC35F4-low versus SLC35F4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35F4→partner) and Y-score (partner→SLC35F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECCT245467 →+0.465+2.807.029.04531
LARGE_INTESTINEFY012 →+0.409+2.871.037.02131
LARGE_INTESTINEJAK3_7406 →+0.494+2.871.010.02131
LARGE_INTESTINEPevonedistat →+0.686+2.871.036.02131
LARGE_INTESTINELIMK1 inhibitor BMS4 →+0.349+3.008.041.01631
LARGE_INTESTINEFTY-720 →+0.203+2.700.038.04731
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CCT245467 by SLC35F4 expression — LARGE_INTESTINE

Box plot of CCT245467 in SLC35F4-low vs SLC35F4-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration