SLC35E2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35E2B mutation is significantly associated with the RNA expression of many other genes, with 2,733 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35E2B-associated genes across cancer lineages are IGHV3OR16-8, CCL5, and LINC02550. Each is linked with SLC35E2B in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35E2B-to-partner and partner-to-SLC35E2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E2B→partner) and Y-score (partner→SLC35E2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECIGHV3OR16-8 →+0.647+3.413<.001<.00131
UCECCCL5 →+1.093+2.758<.001<.00131
UCECLINC02550 →-0.473-3.898.005<.00131
UCECPOM121C →+0.377+3.483.002.00231
UCECMAP3K4-AS1 →+0.733+2.330<.001.00331
UCECDCP1A →+0.525+2.831.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,733 associations by consensus.

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