SLC35E1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35E1 mutation is significantly associated with the RNA expression of many other genes, with 790 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35E1-associated genes across cancer lineages are RN7SL813P, LINC01148, and RN7SL98P. Each is linked with SLC35E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35E1-to-partner and partner-to-SLC35E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL813P grouped by SLC35E1-low versus SLC35E1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E1→partner) and Y-score (partner→SLC35E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL813P →+0.225+5.103<.001.00832
CESCLINC01148 →+0.044+5.306<.001.00632
COADRN7SL98P →+0.274+4.693<.001.00732
UCECRNA5SP419 →+0.676+2.202<.001.00532
UCECRNA5SP410 →+0.646+2.619<.001<.00132
BLCAMIR629 →+0.310+5.147<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 790 associations by consensus.

RN7SL813P by SLC35E1 expression — CESC

Box plot of RN7SL813P in SLC35E1-low vs SLC35E1-high samples in CESC.

Explore this box plot interactively →

Exploration