SLC35E1

Across TCGA pan-cancer cohorts, SLC35E1 RNA is linked to patient survival in 31 of 34 cancer types, making it the most broadly survival-associated SLC35E1 data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher SLC35E1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35E1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

BLCA, ACC, and KIRC are the cancer types where SLC35E1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	II,III,IV	0.266	0.458	.002	59	view →
ACC	DFS	Median	All	0.394	0.752	<.001	54	view →
KIRC	OS	Median	All	0.688	0.572	.005	46	view →
KICH	OS	Median	All	0.836	1.000	.014	44	view →
UVM	DFS	Quartile	III,IV	0.344	0.795	.008	25	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LGG	OS	Median	All	0.751	0.871	<.001	23	view →
HNSC	DFS	Median	IV	0.385	0.215	.013	19	view →
KIRP	OS	Median	II,III,IV	0.527	0.926	.011	18	view →
ESCA	OS	Median	IV	0.222	0.698	.006	12	view →
UCEC	DFS	Median	All	0.802	0.869	.011	12	view →
MESO	DFS	Median	IV	0.226	0.494	.039	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 31 lineages.

SLC35E1–BLCA (DFS)

Open the BLCA breakdown →