SLC35D2

Across TCGA patient cohorts, SLC35D2 mutation is significantly associated with the RNA expression of many other genes, with 2,146 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35D2-associated genes across cancer lineages are MIR7845, SENP3-EIF4A1, and IGLV2-8. Each is linked with SLC35D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D2-to-partner and partner-to-SLC35D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7845 grouped by SLC35D2-low versus SLC35D2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D2→partner) and Y-score (partner→SLC35D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR7845 →	+0.436	+4.034	<.001	.004	3	2
UCEC	SENP3-EIF4A1 →	+0.112	+2.074	<.001	.006	3	1
UCEC	IGLV2-8 →	+2.259	+4.010	<.001	<.001	3	1
UCEC	MIR6803 →	+0.114	+4.019	<.001	.005	3	1
UCEC	GGNBP2 →	+0.365	+3.470	.004	.002	3	1
UCEC	IGHV3-41 →	+0.773	+2.343	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,146 associations by consensus.

MIR7845 by SLC35D2 expression — SKCM

Explore this box plot interactively →