SLC35B2

Across TCGA patient cohorts, SLC35B2 mutation is significantly associated with the RNA expression of many other genes, with 255 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35B2-associated genes across cancer lineages are CYP4F36P, AGPAT5P1, and METTL7AP1. Each is linked with SLC35B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35B2-to-partner and partner-to-SLC35B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYP4F36P grouped by SLC35B2-low versus SLC35B2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B2→partner) and Y-score (partner→SLC35B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CYP4F36P →	+0.096	+4.249	<.001	.007	3	2
COAD	AGPAT5P1 →	+0.126	+6.721	<.001	<.001	3	2
HNSC	METTL7AP1 →	+0.097	+5.655	<.001	.004	3	2
BRCA	KRT18P45 →	+0.072	+4.162	<.001	.001	3	2
UCEC	RPL34P36 →	+0.081	+3.386	.001	.004	3	2
UCEC	TRGJP1 →	+0.921	+3.162	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 255 associations by consensus.

CYP4F36P by SLC35B2 expression — BRCA

Explore this box plot interactively →