SLC35A4

Across TCGA pan-cancer cohorts, SLC35A4 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC35A4 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SLC35A4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC35A4 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where SLC35A4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.885	.018	60	view →
PDAC	DFS	Median	III,IV	0.650	0.290	.006	18	view →
LUAD	DFS	Tertile	II,III,IV	0.212	0.837	.001	14	view →
HNSC	DFS	Quartile	IV	0.927	0.547	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC35A4–COAD (DFS)

Open the COAD breakdown →