SLC35A4

Across TCGA patient cohorts, SLC35A4 RNA expression is significantly associated with the mutation status of many other genes, with 9,751 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A4-associated genes across cancer lineages are PCDHB6, PIK3CA, and TP53. Each is linked with SLC35A4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC35A4-to-partner and partner-to-SLC35A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCDHB6 grouped by SLC35A4-low versus SLC35A4-high in LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A4→partner) and Y-score (partner→SLC35A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PCDHB6 →	+2.291	+0.278	<.001	<.001	3	4
STAD	PIK3CA →	+1.925	+0.281	.001	.002	3	4
BRCA	TP53 →	-0.821	-0.207	<.001	<.001	3	4
STAD	NAV3 →	+2.371	+0.301	.002	.003	3	4
UCEC	VCAN →	+1.427	+0.267	<.001	<.001	3	4
UCEC	TTN →	+0.645	+0.219	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,751 associations by consensus.

PCDHB6 by SLC35A4 expression — LUSC

Explore this box plot interactively →