SLC35A4

Across TCGA patient cohorts, SLC35A4 mutation is significantly associated with the RNA expression of many other genes, with 723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A4-associated genes across cancer lineages are CYCSP26, ELK1P1, and APOBEC3AP1. Each is linked with SLC35A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A4-to-partner and partner-to-SLC35A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYCSP26 grouped by SLC35A4-low versus SLC35A4-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A4→partner) and Y-score (partner→SLC35A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	CYCSP26 →	+0.140	+6.528	<.001	.001	3	2
SKCM	ELK1P1 →	+0.099	+4.075	<.001	.004	3	2
SKCM	APOBEC3AP1 →	+0.190	+3.875	.001	.006	3	2
BLCA	MTCO2P4 →	+0.262	+5.411	<.001	.005	3	2
UCEC	RNA5SP415 →	+0.335	+1.903	.007	.009	3	2
LUSC	FAM243A →	+0.038	+5.148	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 723 associations by consensus.

CYCSP26 by SLC35A4 expression — KIRP

Explore this box plot interactively →