SLC35A4

Across TCGA patient cohorts, SLC35A4 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A4-associated genes across cancer lineages are Notch1, 14-3-3_beta, and A-Raf_pS299. Each is linked with SLC35A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A4-to-partner and partner-to-SLC35A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by SLC35A4-low versus SLC35A4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A4→partner) and Y-score (partner→SLC35A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.114	+1.584	.040	.036	3	2
UCEC	14-3-3_beta →	-0.107	-2.295	.006	.033	3	1
UCEC	A-Raf_pS299 →	-0.219	-3.700	<.001	.001	3	1
UCEC	Fibronectin →	-0.256	-2.502	.048	.002	3	1
UCEC	FoxM1 →	+0.205	+1.584	.043	.036	3	1
UCEC	FOXO3a_pS318_S321 →	-0.102	-2.105	.037	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Notch1 by SLC35A4 expression — UCEC

Explore this box plot interactively →