SLC35A4

Across TCGA cell cohorts, SLC35A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,891 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC35A4-associated GO terms across cancer lineages are Regulation of protein sumoylation, DNA replication-dependent chromatin assembly, and Chromosome condensation. Each is linked with SLC35A4 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC35A4-to-partner and partner-to-SLC35A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein sumoylation grouped by SLC35A4-low versus SLC35A4-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A4→partner) and Y-score (partner→SLC35A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of protein sumoylation →	+0.136	+0.939	<.001	<.001	3	13
BONE	DNA replication-dependent chromatin assembly →	+0.125	+0.598	.001	<.001	3	13
SOFT_TISSUE	Chromosome condensation →	+0.181	+1.057	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.077	+1.003	<.001	<.001	3	12
LARGE_INTESTINE	CAAX-box protein maturation →	+0.140	+0.914	<.001	<.001	3	12
PANCREAS	Negative regulation of cell cycle phase transition →	+0.060	+1.191	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,891 associations by consensus.

Regulation of protein sumoylation by SLC35A4 expression — LARGE_INTESTINE

Explore this box plot interactively →