SLC35A4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35A4 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC35A4-associated genes across cancer lineages are CCL1, TEX55, and ACSM6. Each is linked with SLC35A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A4-to-partner and partner-to-SLC35A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL1 grouped by SLC35A4-low versus SLC35A4-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A4→partner) and Y-score (partner→SLC35A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSCCL1 →+0.427+4.472<.001.00431
CNSTEX55 →+0.037+4.321<.001.00931
LARGE_INTESTINEACSM6 →+0.027+4.169<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CCL1 by SLC35A4 expression — CNS

Box plot of CCL1 in SLC35A4-low vs SLC35A4-high samples in CNS.

Explore this box plot interactively →

Exploration