SLC35A2

Across TCGA cell cohorts, SLC35A2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35A2-associated genes across cancer lineages are CLDN17, GKN1, and NUPR2. Each is linked with SLC35A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A2-to-partner and partner-to-SLC35A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLDN17 grouped by SLC35A2-low versus SLC35A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A2→partner) and Y-score (partner→SLC35A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CLDN17 →	+0.066	+4.930	<.001	.001	3	1
LARGE_INTESTINE	GKN1 →	+0.077	+4.095	<.001	.009	3	1
LARGE_INTESTINE	NUPR2 →	+0.376	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TBC1D3 →	+0.080	+4.273	<.001	.006	3	1
LARGE_INTESTINE	F11 →	+0.057	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CLDN17 by SLC35A2 expression — LARGE_INTESTINE

Explore this box plot interactively →