SLC34A3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC34A3 mutation is significantly associated with the RNA expression of many other genes, with 643 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC34A3-associated genes across cancer lineages are RNA5SP264, RNU6-956P, and ZNF519P4. Each is linked with SLC34A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC34A3-to-partner and partner-to-SLC34A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A3→partner) and Y-score (partner→SLC34A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNA5SP264 →+0.350+5.339<.001.00332
SKCMRNU6-956P →+1.104+4.469<.001.00632
SKCMZNF519P4 →+0.410+4.867<.001<.00132
COADLINC02751 →+0.194+3.899.002.00332
BLCAUSP17L3 →+0.019+7.640<.001.00932
BLCAMTCO2P3 →+0.079+7.640<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 643 associations by consensus.

Exploration