Across TCGA patient cohorts, SLC34A3 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC34A3-associated genes across cancer lineages are eEF2, EGFR_pY1068, and GAPDH. Each is linked with SLC34A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC34A3-to-partner and partner-to-SLC34A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A3→partner) and Y-score (partner→SLC34A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.329	+2.999	.048	.035	3	1
UCEC	EGFR_pY1068 →	-0.329	-3.321	.004	.010	3	1
UCEC	GAPDH →	+0.496	+3.000	.047	.036	3	1
UCEC	HSP70 →	-0.392	-2.990	.036	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.239	-3.459	.002	.005	3	1
UCEC	NDRG1_pT346 →	-0.465	-2.321	.042	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

SLC34A3 survival (RNA) · tumor vs normal (RNA) · all SLC34A3 data types