SLC33A1

Across TCGA patient cohorts, SLC33A1 mutation is significantly associated with the RNA expression of many other genes, with 2,623 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC33A1-associated genes across cancer lineages are E2F6P1, LARP1, and STOML2. Each is linked with SLC33A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC33A1-to-partner and partner-to-SLC33A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, E2F6P1 grouped by SLC33A1-low versus SLC33A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC33A1→partner) and Y-score (partner→SLC33A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	E2F6P1 →	+0.023	+3.179	<.001	.007	3	3
UCEC	LARP1 →	+0.430	+2.455	.001	.001	3	2
UCEC	STOML2 →	+0.419	+2.542	.002	<.001	3	2
UCEC	MELK →	+0.772	+3.010	<.001	<.001	3	2
UCEC	LMNB2 →	+0.721	+3.643	<.001	<.001	3	2
UCEC	NLE1 →	+0.547	+2.534	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,623 associations by consensus.

E2F6P1 by SLC33A1 expression — SKCM

Explore this box plot interactively →