SLC32A1

Across TCGA patient cohorts, SLC32A1 mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC32A1-associated genes across cancer lineages are FASN, PRDX1, and p62 Lck ligand. Each is linked with SLC32A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC32A1-to-partner and partner-to-SLC32A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by SLC32A1-low versus SLC32A1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC32A1→partner) and Y-score (partner→SLC32A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	FASN →	+0.675	+3.000	.013	.036	3	2
BLCA	PRDX1 →	+0.324	+2.820	.007	.035	3	2
LUAD	p62 Lck ligand →	+0.584	+2.186	.010	.034	3	2
UCEC	eEF2 →	+0.242	+1.321	.043	.029	3	2
COAD	FoxM1 →	+0.340	+2.008	.018	.018	3	2
UCEC	FOXO3a_pS318_S321 →	-0.110	-1.492	.008	.027	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

FASN by SLC32A1 expression — BLCA

Explore this box plot interactively →