SLC32A1

Across TCGA cell cohorts, SLC32A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 735 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC32A1-associated GO terms across cancer lineages are mRNA transport, Positive regulation of membrane protein ectodomain proteolysis, and RNA localization. Each is linked with SLC32A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC32A1-to-partner and partner-to-SLC32A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA transport grouped by SLC32A1-low versus SLC32A1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC32A1→partner) and Y-score (partner→SLC32A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	mRNA transport →	+0.055	+1.155	.009	.002	3	4
LUNG_SCLC	Positive regulation of membrane protein ectodomain proteolysis →	-0.144	-1.103	<.001	.004	3	4
LUNG_SCLC	RNA localization →	+0.045	+1.117	.008	.003	3	4
BLOOD_Leukemia	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.029	+0.205	.001	.007	3	4
BLOOD_Leukemia	mRNA splicing, via spliceosome →	+0.029	+0.205	.001	.007	3	4
LUNG_SCLC	Intermembrane phospholipid transfer →	+0.136	+1.228	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 735 associations by consensus.

mRNA transport by SLC32A1 expression — LUNG_SCLC

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