SLC32A1

Across TCGA cell cohorts, SLC32A1 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC32A1-associated genes across cancer lineages are OR10Q1, DYNAP, and AWAT2. Each is linked with SLC32A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC32A1-to-partner and partner-to-SLC32A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10Q1 grouped by SLC32A1-low versus SLC32A1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC32A1→partner) and Y-score (partner→SLC32A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10Q1 →	+0.490	+4.643	<.001	.004	3	3
BLOOD_Lymphoma	DYNAP →	+0.071	+4.867	.002	.009	3	2
LUNG_NSCLC_LUSC	AWAT2 →	+0.016	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUAD	GJA8 →	+0.493	+4.149	<.001	<.001	3	1
LUNG_NSCLC_LUAD	STOML3 →	+0.125	+4.933	<.001	<.001	3	1
LUNG_NSCLC_LUAD	TAS2R60 →	+0.071	+3.980	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

OR10Q1 by SLC32A1 expression — LUNG_SCLC

Explore this box plot interactively →