SLC30A8

Across TCGA cell cohorts, SLC30A8 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC30A8-associated genes across cancer lineages are C14orf180, SCGB2A1, and ASB10. Each is linked with SLC30A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A8-to-partner and partner-to-SLC30A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C14orf180 grouped by SLC30A8-low versus SLC30A8-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A8→partner) and Y-score (partner→SLC30A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C14orf180 →	+0.026	+4.273	<.001	.006	3	2
BLOOD_Leukemia	SCGB2A1 →	+0.047	+5.201	<.001	.006	3	1
STOMACH	ASB10 →	+0.012	+4.285	<.001	.007	3	1
LARGE_INTESTINE	CUEDC2 →	+0.816	+3.064	<.001	.009	3	1
LARGE_INTESTINE	C1QBP →	+0.976	+3.131	<.001	.008	3	1
LARGE_INTESTINE	MS4A4A →	+0.147	+2.678	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

C14orf180 by SLC30A8 expression — SKIN

Explore this box plot interactively →