SLC30A7

Across TCGA pan-cancer cohorts, SLC30A7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC30A7 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC30A7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC30A7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, PDAC, and LSCC are the cancer types where SLC30A7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.907	0.608	.002	49	view →
PDAC	OS	Median	II,III,IV	0.402	0.642	.010	14	view →
LSCC	OS	Median	II,III,IV	0.688	0.941	.006	8	view →
CCRCC	DFS	Quartile	All	0.924	0.309	.027	6	view →
GBM	DFS	Median	All	0.643	0.844	.008	5	view →
LUAD	OS	Quartile	III,IV	1.000	0.381	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC30A7–HNSC (DFS)

Open the HNSC breakdown →