SLC30A7

Across TCGA patient cohorts, SLC30A7 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A7-associated genes across cancer lineages are Notch1, EGFR_pY1068, and GAPDH. Each is linked with SLC30A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A7-to-partner and partner-to-SLC30A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by SLC30A7-low versus SLC30A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A7→partner) and Y-score (partner→SLC30A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.183	+3.179	.007	.010	3	2
UCEC	EGFR_pY1068 →	-0.319	-3.584	.008	.002	3	1
UCEC	GAPDH →	+0.513	+2.999	.047	.035	3	1
UCEC	GATA6 →	-0.198	-3.000	.008	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.217	-2.999	.007	.035	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.535	-2.446	.013	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Notch1 by SLC30A7 expression — UCEC

Explore this box plot interactively →