SLC30A6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC30A6 mutation is significantly associated with the RNA expression of many other genes, with 1,813 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A6-associated genes across cancer lineages are GAGE13, RNU6-1272P, and RNU6-1195P. Each is linked with SLC30A6 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC30A6-to-partner and partner-to-SLC30A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE13 grouped by SLC30A6-low versus SLC30A6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A6→partner) and Y-score (partner→SLC30A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAGAGE13 →+0.165+4.433<.001.00733
BLCARNU6-1272P →+0.332+3.799<.001.00732
BLCARNU6-1195P →+0.213+4.433<.001.00732
SKCMVN1R17P →+0.056+3.979<.001.00332
BLCAMRPL49P2 →+0.194+5.341<.001<.00132
BLCACASP1P1 →+0.205+4.112<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,813 associations by consensus.

GAGE13 by SLC30A6 expression — BLCA

Box plot of GAGE13 in SLC30A6-low vs SLC30A6-high samples in BLCA.

Explore this box plot interactively →

Exploration