SLC30A3

Across TCGA patient cohorts, SLC30A3 mutation is significantly associated with the RNA expression of many other genes, with 2,072 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A3-associated genes across cancer lineages are RNA5SP412, CRYBB2P1, and SUV39H1. Each is linked with SLC30A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC30A3-to-partner and partner-to-SLC30A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by SLC30A3-low versus SLC30A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A3→partner) and Y-score (partner→SLC30A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.648	+2.329	<.001	<.001	3	3
UCEC	CRYBB2P1 →	+0.422	+2.385	.004	.002	3	2
SKCM	SUV39H1 →	+0.409	+3.468	.004	.002	3	2
UCEC	NFKBIB →	+0.483	+2.747	<.001	<.001	3	2
SKCM	CARS1 →	+0.487	+3.478	.002	.002	3	2
SKCM	FOXM1 →	+0.835	+3.331	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,072 associations by consensus.

RNA5SP412 by SLC30A3 expression — UCEC

Explore this box plot interactively →