SLC30A3

Across TCGA cell cohorts, SLC30A3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC30A3-associated genes across cancer lineages are GP2 and CRISP1. Each is linked with SLC30A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A3-to-partner and partner-to-SLC30A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GP2 grouped by SLC30A3-low versus SLC30A3-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A3→partner) and Y-score (partner→SLC30A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GP2 →	+0.045	+4.108	<.001	.005	3	1
LARGE_INTESTINE	CRISP1 →	+0.014	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GP2 by SLC30A3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →