SLC2A9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC2A9 mutation is significantly associated with the RNA expression of many other genes, with 1,423 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A9-associated genes across cancer lineages are RNU4-49P, RNU7-103P, and RN7SL517P. Each is linked with SLC2A9 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC2A9-to-partner and partner-to-SLC2A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-49P grouped by SLC2A9-low versus SLC2A9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A9→partner) and Y-score (partner→SLC2A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRNU4-49P →+0.261+3.086<.001.00134
COADRNU7-103P →+0.519+4.478<.001<.00133
LUSCRN7SL517P →+0.181+4.031<.001.00433
UCECSCOC →+0.483+1.856.003.00432
UCECHEATR3 →+0.353+1.470.007.00832
UCECCIAO2B →+0.380+3.917<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,423 associations by consensus.

RNU4-49P by SLC2A9 expression — LUAD

Box plot of RNU4-49P in SLC2A9-low vs SLC2A9-high samples in LUAD.

Explore this box plot interactively →

Exploration