SLC2A9

Across TCGA pan-cancer cohorts, SLC2A9 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SLC2A9’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where SLC2A9 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC2A9 is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, HNSC, and LUAD are the cancer types where SLC2A9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC2A9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−2.882	<.001	11	view →
HNSC	Female	III,IV	+1.839	<.001	11	view →
LUAD	Male	II,III,IV	−0.780	<.001	11	view →
THCA	All	IV	−1.272	<.001	10	view →
BRCA	Female	All	−0.590	<.001	6	view →
LIHC	All	All	−0.721	<.001	4	view →
CHOL	Female	All	−2.493	<.001	3	view →
PRAD	All	All	−1.215	<.001	2	view →
COAD	Male	II,III,IV	+0.324	.018	1	view →
LUSC	All	All	+0.322	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SLC2A9–KICH

Open the KICH breakdown →