SLC2A9

Across TCGA patient cohorts, SLC2A9 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A9-associated genes across cancer lineages are EGFR_pY1068, ASNS, and HSP70. Each is linked with SLC2A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A9-to-partner and partner-to-SLC2A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by SLC2A9-low versus SLC2A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A9→partner) and Y-score (partner→SLC2A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.207	-1.874	.025	.049	3	2
UCEC	ASNS →	+0.310	+2.321	.019	.033	3	2
UCEC	HSP70 →	-0.346	-1.502	.019	.030	3	1
UCEC	mTOR_pS2448 →	-0.130	-1.787	.017	.026	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.428	-1.807	.009	.025	3	1
UCEC	14-3-3_epsilon →	+0.083	+2.247	.023	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

EGFR_pY1068 by SLC2A9 expression — UCEC

Explore this box plot interactively →